Clinically grounded. Safe by design

Second Brain combines guideline-aligned logic, IRB-validated methods, clinician
oversight, and always-on safety rails to keep GI navigation accurate, explainable, and safe.

Clinical foundations

  • Built on an IRB-validated diagnostic framework

  • Aligns with leading GI guidelines (e.g., major GI societies, Rome criteria)

  • Developed with input from GI clinicians and registered dietitians

  • Regularly reviewed and updated as evidence evolves

Our goal: Bring diagnostic-first discipline to GI navigation in a way that works for both members and employers.

How our evidence engine works

When employees answer questions, our engine:

  • Uses those responses to update probabilities across a governed set of GI conditions

  • Weighs symptoms and patterns against current evidence and clinical logic

  • Produces a transparent, auditable recommendation that supports our clinical team

It’s not a black-box score. It’s a structured, evidence-backed way to support better first decisions.

Safety rails at every step

1.

Red-flag screening

Symptoms and combinations known to indicate higher risk are prioritized and escalated quickly.

2.

Recovery system

The system detects ambiguous or conflicting answers and re-checks them with the employee to avoid misinterpretation.

3.

Clinician oversight

Care plans are reviewed under medical supervision, and escalation to GI or PCP follows clear, documented criteria.

4.

Escalation pathways

When signals warrant it, employees are guided toward the right clinician at the right time—not left to figure it out alone.

What this means for employers

  • Confidence that GI navigation is safe, repeatable, and evidence-based

  • A clear story for internal stakeholders on how decisions are made

  • Fewer surprises from missed red flags or unnecessary escalations

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